MTE 23.01 Thymic Neoplasms

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Well-Differentiated Thymic Epithelial Neoplasms (Thymoma)

(atypical thymoma); and those showing total loss of the organotypical features of the thymus and displaying overt cytologic evidence of malignancy correspond to high-grade or poorly differentiated thymic epithelial neoplasms (also designated, by convention, thymic carcinoma) (2,4). The grading is based on a combination of architectural and cytological parameters as observed on routine microscop...

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A serological study of primary thymic neoplasms.

New insight into the immunological function of the thymus has added to the significance of the rare primary neoplasms of this organ. It has long been known that thymomas are associated with a high incidence of certain systemic diseases, the best recognized of which are myasthenia gravis (Castleman, 1955), pure red-cell aplasia (Havard and Scott, 1960), and hypo-y-globulinaemia (Gafni, Michaeli,...

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Thymic Neuroendocrine Neoplasms: Biological Behaviour and Therapy.

Thymic neuroendocrine neoplasms are rare tumours, but their management can often be highly problematic. While previously assumed to be essentially variants of bronchopulmonary (lung) carcinoids, they are generally more aggressive and more difficult to treat. Some 25% are associated with multiple endocrine neoplasia-1, while a higher proportion are associated with the ectopic ACTH syndrome, and ...

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Current chemotherapy options for thymic epithelial neoplasms.

Thymomas and thymic carcinoma are rare neoplasms. Surgical resection is the cornerstone of effective therapy. Stage I disease is effectively treated by complete surgical resection. The role of radiation therapy in completely resected stage II disease remains controversial. Adjuvant radiation therapy is useful for local control and may improve survival in patients with incompletely resected tumo...

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Management of Thymic Neoplasms: Egyptian NCI Experience

Background: Thymic tumors are rare entity with little information regarding outcomes after therapy with curative intent. They are heterogeneous group of neoplastic lesions with wide spectrum of morphologic appearances. They show different presentations with a variable & unpredictable evolution ranging from indolent attitude to highly infiltrative and metastasizing one. The optimal treatment inc...

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ژورنال

عنوان ژورنال: Journal of Thoracic Oncology

سال: 2017

ISSN: 1556-0864

DOI: 10.1016/j.jtho.2017.09.174